ZIP Code 53221 — Milwaukee, WI Home Prices (2026)

The typical home in ZIP 53221 (Milwaukee, Wisconsin) is worth about $299,000 at roughly $209 per square foot — 29% more expensive than the Milwaukee median and 2% more expensive than the typical U.S. home.

$299,000

Typical home value

$209

Price per sq ft

#4 of 20

Milwaukee ZIPs by value

+29%

vs Milwaukee median

How 53221 compares

ZIP 53221 is one of the pricier ZIP codes in Milwaukee: its typical home value of $299,000 ranks #4 of the 20 Milwaukee ZIP codes we track (the citywide range runs from $97,000 in 53206 to $386,000 in 53203). Per square foot it costs about $209, against $162 for Milwaukee as a whole, $209 for Wisconsin, and $195 nationally.

Area	Typical value	$ / sq ft
ZIP 53221	$299,000	$209
Milwaukee, WI	$232,500	$162
Wisconsin	$317,000	$209
United States	$294,000	$195

Home value by size in 53221

Using this ZIP’s rate of about $209 per square foot. Condition, lot, and the exact street move these meaningfully — use the estimator below for a home-specific figure.

Home size	Estimated value
1,000 sq ft	$209,000
1,500 sq ft	$313,500
2,000 sq ft	$418,000
2,500 sq ft	$522,500
3,000 sq ft	$627,000

Salary needed to buy a home in ZIP 53221

To buy the typical $299,000 home in ZIP 53221 with 20% down, you need a household income of roughly $81,000 a year (about $1,900 a month for the mortgage, taxes, and insurance). With 10% down the bar rises to about $97,000, because the loan is bigger and mortgage insurance kicks in.

Down payment	Cash down	Monthly payment	Income needed
5% (+PMI)	$15,000	$2,360/mo	$101,000/yr
10% (+PMI)	$29,900	$2,260/mo	$97,000/yr
20%	$59,800	$1,900/mo	$81,000/yr

Assumes a 30-year fixed mortgage at 6.5%, property tax at 1.1% and insurance at 0.45% of value per year, PMI of 0.75% on loans with less than 20% down, and the standard 28% housing-to-income rule. Your rate, taxes, and HOA will move these — run your own numbers in the mortgage calculator.

What your budget buys in ZIP 53221

At about $209 per square foot, here is roughly how much home different budgets get you in ZIP 53221:

Budget	Approx. size	What that looks like locally
$150k	720 sq ft	below the local median — condos, smaller or older homes
$200k	960 sq ft	below the local median — condos, smaller or older homes
$250k	1200 sq ft	around the typical home here
$300k	1440 sq ft	around the typical home here
$400k	1910 sq ft	above the median — larger homes or the pricier ZIPs

Wondering where that budget goes further? The relocation calculator ranks hundreds of U.S. cities by what the same money buys — it opens pre-filled with a typical 53221 home.

Estimate a specific home in 53221

The estimator below is pre-set to ZIP 53221 — pick your home’s size for an instant ballpark, then open the full calculator to adjust beds, baths, and condition.

All Milwaukee ZIP codes by home value

Where 53221 sits among Milwaukee’s 20 ZIP codes:

#	ZIP code	Typical value	$ / sq ft
1	53203	$386,000	$355
2	53202	$370,000	$308
3	53207	$315,000	$237
4	53221 (this page)	$299,000	$209
5	53219	$277,000	$221
6	53222	$273,000	$197
7	53224	$248,000	$168
8	53225	$243,000	$173
9	53208	$240,000	$155
10	53223	$238,000	$150
11	53215	$227,000	$150
12	53212	$218,000	$186
13	53233	$188,000	$127
14	53216	$180,000	$141
15	53210	$172,000	$124
16	53218	$171,000	$149
17	53209	$170,000	$142
18	53204	$166,000	$221
19	53205	$158,000	$147
20	53206	$97,000	$80

ZIP 53221 home prices: frequently asked

What is the average home price in ZIP code 53221? +

The typical home in ZIP 53221 (Milwaukee, WI) is worth about $299,000 as of 2026. That is 29% more expensive than the Milwaukee median of $232,500 and 2% more expensive than the U.S. median of $294,000.

What is the price per square foot in 53221? +

About $209 per square foot in 53221, versus $162 across Milwaukee and $209 across Wisconsin. At that rate a 1,500 sq ft home runs roughly $313,500 and a 2,500 sq ft home about $522,500.

What salary do you need to buy a house in ZIP 53221? +

For the typical $299,000 home in ZIP 53221, a household income of about $81,000 a year covers the payment with 20% down (a 30-year fixed at 6.5%, plus taxes and insurance, under the 28% rule). With 10% down you need roughly $97,000; with 5% down about $101,000.

Is 53221 an expensive ZIP code? +

Within Milwaukee, 53221 ranks #4 of 20 ZIP codes by typical home value, which makes it one of the pricier ZIP codes in Milwaukee. Nationally it is about average.

See the full Milwaukee home values page, all Wisconsin cities, or price per square foot by ZIP code nationwide.

Directional estimates from public market data (Realtor.com & Zillow research), not appraisals. A single ZIP contains very different homes; actual values vary and change over time.